The failure of the U.S.-Iran negotiations that took place in Pakistan marks a decisive inflection point in the current Middle Eastern security course. This is not a diplomatic setback; it is the transition from a fragile de-escalation phase into a more volatile period defined by coercive pressure, military signaling, and elevated risk of miscalculation. This risk is driven by the threat Iran continues to pose to freedom of navigation in the Strait of Hormuz and by its remaining ballistic capabilities, which allow it to erratically target neighboring Arab states and regional U.S. allies.

Furthermore, the announcement of a U.S.-led maritime blockade over Iranian ports fundamentally alters the operational and strategic landscape aimed at confining the Iranian threat. The main question now is no longer whether tensions will rise, they already have, but whether the current trajectory leads toward controlled escalation, negotiated recalibration, or systemic full-scale conflict.

Structural Drivers of Escalation

At the core of the U.S.-Iran negotiations lies a set of structural but irreconcilable objectives. The U.S. continues to frame its demands around three pillars: curtailment of Iran’s nuclear development program, limitations on ballistic missile capabilities development, and the rollback of Iran’s regional proxy networks. Iran, on the opposite side, views these elements as essential to regime survival and sovereign deterrence. Accordingly, this is not a negotiation gap; it is a strategic contradiction.

Iran’s nuclear posture has evolved from a bargaining chip into a core pillar of the Iran’s Islamic Revolutionary Guard Corps’ (IRGC) and the regime’s survival. Any perceived concession risks undermining internal legitimacy and external deterrence credibility. Accordingly, ongoing diplomatic negotiations are performative rather than transformative, thus aimed at managing escalation rather than resolving underlying disputes. Additionally, the U.S. decision to impose a maritime blockade represents a calibrated escalation designed to exert economic and psychological pressure without the need to immediately resort back to kinetic operations. However, the strategic implications are profound.

Iran’s economy relies mainly on maritime oil exports. A blockade directly targets this vulnerability, threatening revenue streams, which then impacts the domestic stability, in addition to regional influence operations funded through such revenues. From Tehran’s perspective, failure to respond would signal weakness not only to the U.S. but also to its network of non-state groups across the region. This creates a classic escalation dilemma for Iran. On one hand, not responding risks strategic erosion of the IRGC and the current regime’s image. On the other hand, the response risks triggering military confrontation, which Iran cannot withstand. In such conditions, even any Iranian action such as harassment of commercial shipping, or proxy attacks carry a high probability of escalation.

Another key driver for the escalation is the pre-positioned military capabilities. Unlike previous crises, the current environment is characterized by pre-positioned military assets and operational readiness on both sides. U.S. naval, air, and ground forces in the Middle East are already configured for rapid response operations, while Iran’s IRGC maintains asymmetric capabilities are carefully tailored for maritime disruption, drone attacks, ballistic missile launches, and regional proxy warfare.

Regional Spillover Risks

The Strait of Hormuz remains the most critical geographic variable in this confrontational equation given that one-fifth of global oil trade passes through this narrow waterway. Iran has long signaled its capability and strategic intent to disrupt traffic through asymmetric means, including naval mines, drones, and anti-ship missiles. While full closure remains unlikely due to the overwhelming U.S. response it would provoke, disruption has already been taking place via targeted attacks on passing vessels, which is more than enough to deter commercial liners. Even limited interference could generate outsized economic and political effects, particularly for energy-dependent economies. All that said, the Houthis in Yemen remain on standby mode to disrupt the maritime flow via resumption of attacks on vessels passing via Bab-el Mandeb to and from the Red Sea.

Iran’s strategic depth lies not in conventional military parity but in its network of regional proxies. Groups aligned with Tehran, including those in Iraq, Syria, Lebanon, and Yemen, provide Iran with operational flexibility. Given Israel’s successful campaign in Lebanon against Hezbollah as well as the Iran-backed Iraqi militias preoccupied with the deterrence posed by the U.S. forces, the Houthis in Yemen remain the final card for Tehran. Intensified maritime threats from Houthi forces in the Red Sea are likely to reemerge at any moment. This allows Iran to impose costs on U.S. and allied interests without triggering immediate large-scale retaliation. However, the cumulative effect of a multi-chokepoint pressure strategy could compel a broader and internationally supported response.

Strategic Calculus: War vs. Controlled Escalation

Some believe that neither the U.S. nor Iran appears to seek full-scale war given that the costs (military, economic, and political) would be immense and unpredictable. For the U.S., a major conflict with Iran would disrupt global energy markets, divert resources from strategic competition with China, and risk regional destabilization affecting key allies in the Gulf Corporation Council (GCC). For Iran, a continuation of a direct war would expose critical infrastructure to sustained strikes and threaten regime survivability.

The most probable scenario over the next 2–3 weeks is a phase of controlled escalation characterized by maritime harassment incidents in the Gulf, limited proxy attacks, and intensified rhetoric and signaling. This scenario allows both sides to demonstrate resolve while avoiding irreversible steps toward war. However, it is susceptible to disruption by unforeseen incidents at any moment.

An increasingly possible scenario would be one that involves targeted military actions, such as U.S. strikes on IRGC assets or critical infrastructure vs. Iranian retaliatory indiscriminate strikes on U.S. regional allies. Such exchanges would likely be calibrated to avoid full-scale war but could easily escalate if casualties or strategic assets are impacted.

Lastly, a less likely but still possible scenario is the return to productive negotiations, driven by economic pressures including oil market volatility, as well as diplomatic intervention by third parties, including the Gulf states, China, or European actors.

The highest-impact and most consequential scenarios involve a rapid escalation into full-scale conflict, potentially triggered by Iran’s full refusal to give up on its nuclear program or ballistic missile development program. Other triggers for a full-scale conflict would include any major incident in the Strait of Hormuz, high-casualty attacks on U.S. forces, or a direct confrontation between U.S. and Iranian military assets. Such a conflict would likely expand beyond bilateral engagement, drawing in regional actors and severely disrupting global economic systems.

Key Indicators to Watch

Several indicators are going to be crucial in assessing the trajectory of the ongoing conflict. This includes maritime activity where increased Iranian harassment of shipping continues to take place. Proxy operations are also a critical indicator where the frequency and intensity of proxy attacks, and the Red Sea specifically start to rise. Finally, force posture changes remain one of the key indicators, as they are mostly based on advanced intelligence assessments, which are not available to the public or markets. That said, deployment of additional U.S. and allied assets to the region remains the clearest indicator of how the situation will move forward and provides early signs of shifts from controlled escalation to broader conflict.

For defense strategists, the imperative is clear: preparing for escalation, planning for contingencies across multiple theaters, and achieving consensus that in the current environment, the most dangerous outcomes are not those that are intended but those unintended.

Dr. Mohamed ELDoh is a business development and consulting professional in the defense and security sector. Mohamed holds a Doctorate degree from Grenoble École de Management – France, an MBA from the EU Business School- Spain, and an Advanced Certificate in Counterterrorism Studies from the University of St Andrews, UK. He regularly authors articles addressing defense cooperation, counterterrorism, geopolitics, and emerging security threats in the Middle East and Africa. The views of the author are his own.

The Escalation Trajectory of U.S.-Iran Tensions After the Collapse of the Negotiations was originally published on Global Security Review.

Nonproliferation has been the goal of America’s foreign policy since the end of the Cold War more than three decades ago. At that time, the biggest concern was the possibility of the crumbling Soviet military apparatus being captured by rogue states, terrorist organizations, and other non-friendly entities that could use Soviet expertise and technological prowess to develop means to attack the United States. The Cooperative Threat Reduction Program (CTR), for instance, was started in 1991 to assist the Soviet Union and its “successor entities” to “destroy nuclear, chemical, and other weapons; transport, store, disable, and safeguard weapons in connection with their destruction; and establish verifiable safeguards against the proliferation of such weapons.”

Since then, many more programs have been created to control exports of sensitive and dual-use materials. Regardless of the effectiveness of these programs, it might seem that the world has entered a new era of proliferation as allies and partners, among others, start to question the security commitments of the United States and the possible prospect of developing their own nuclear programs.

Whether the US would actively defend its allies and partners if attacked, thousands of miles away from American territory, has long stimulated debate. Now, more than ever, Ukraine and the Middle East are important centers of attention following their years-long conflicts and the involvement of the United States. In Ukraine, for instance, President Trump called for peace negotiations, allegedly, without the consent of Ukraine.

Amid these decisions, conflicting messages were shared by American officials on the issue. On the one hand, President Trump stated that “Ukraine may be Russian one day, or not,” and that there were discussions on the possibility of a deal to provide the United States with part of Ukraine’s mineral deposits in exchange for American weapons. On the other hand, Secretary of Defense Pete Hegseth stated that North Atlantic Treaty Organization (NATO) membership for Ukraine is unrealistic and that the country should abandon its hopes of a return to its pre-2014 borders.

The fears running among Ukrainians and other European partners are shared. What if the US withdraws its assistance from Ukraine? What about the rest of the continent? On Monday, February 17, 2025, European leaders met to form a united front during an emergency meeting in Paris to discuss Trump’s plans for Ukraine and the continent. In this meeting, the reliability of Europe’s key transatlantic partner might be questioned. As this situation and the negotiations continue, many possible outcomes are certain to receive attention.

One of them includes the possibility of developing or expanding European nuclear programs, which is an idea floated for some time. For instance, Elena Davlikanova, from the Center for European Policy Analysis, reported that “[d]uring his speech in Brussels on October 17, Ukrainian President Zelenskyy voiced what many Ukrainians are thinking, that in the war for its existence, Ukraine now has a choice between NATO membership or manufacturing nuclear weapons.” If, according to the US Secretary of Defense, Ukraine’s membership in NATO is dismissed, then the other viable option for Kyiv is clear. And so might be for other US partners and allies.

In the Middle East, furthermore, a similar situation could be addressed. Since the last violent exchanges between Israel and Iran, concerns were raised about the possibility that Iran may now finally develop its own nuclear program with the assistance of Russia. Moreover, President Trump’s plans to expel ethnic Palestinians from Gaza and turn it into the “Riviera of the Middle East” could fuel concerns among Arab partners.

Along these lines, Arab states, friend or foe of the US, may acquire nuclear capabilities if they perceive their interests (regime survival, national integrity, sovereignty, etc.) are at stake and if they consider the growing US-Israel alliance a security risk. Iran could definitely see it this way, but what about the newly established Syrian government? The historical competition between Israel and Syria could now further expand as Islamist organizations now control the country.

Overall, two roads seem to be ahead of us. If the Trump administration’s goal is to partially denuclearize China and Russia, then concessions (“sacrifices”) will need to be made, which might include surrendering Ukraine to Moscow and, perhaps, Taiwan to Beijing—or at least the sovereignty claims of the South China Sea. If this is the case, the US alliance may tremble, encouraging US partners and allies to pursue their own independent nuclear programs. The other road leads to the support of US partners and allies but without facing real possibilities of engaging in arms control negotiations with either China or Russia.

In other words, the status quo would be maintained. The Trump administration would need to start evaluating these two paths ahead, but partners and allies should also play their part to convince the administration that they are not a burden to carry, and that keeping the alliance alive will also benefit the United States in the short and long term.

Santiago Spadiliero is a doctoral candidate at Missouri State University’s School of Defense and Strategic Studies whose research is focused on great power competition, deterrence, and America’s missile defense architecture.

President Trump’s Foreign Policy Could Encourage Proliferation was originally published on Global Security Review.